Final answer:
Peptidomimetics can be used to synthesize artificial compounds that mimic the effects of a protein influencing headaches.
Step-by-step explanation:
To synthesize a new artificial compound that mimics the effects of a known protein influencing headaches, scientists can utilize a rational design approach known as peptidomimetics. Peptidomimetics are molecules that mimic the bioactive conformation of peptides and retain the ability to interact with the biological target and cause the same biological effect. By transforming peptides into low-molecular-weight and bioavailable drug-like molecules, peptidomimetics offer improved pharmacokinetic properties.
For example, introducing modifications or employing different administration routes of peptide-based therapeutics can overcome the limitations of peptides. Additionally, rational design based on step-wise transformation of peptides has resulted in approved drugs such as protease inhibitors. This approach can be applied to develop compounds that mimic the effects of the protein influencing headaches.