Final answer:
Shaking IgG instead of swirling gently can lead to the denaturation of the protein, affecting its structure and immune function.
Step-by-step explanation:
If IgG is shaken instead of swirled gently, denaturation can result. Proteins can be denatured through physical agitation, which leads to a loss of their three-dimensional structure and function. While actions such as shaking might also cause other processes, such as agglutination or precipitation, denaturation refers specifically to the change induced in the structure of the IgG molecule itself, potentially affecting its ability to function properly within immune responses.