In the presence of oxygen, pyruvate is transformed into an acetyl group attached to a carrier molecule of coenzyme A. This process produces carbon dioxide and high energy electrons, which are carried by NADH.
In the presence of oxygen, pyruvate is transformed into an acetyl group attached to a carrier molecule of coenzyme A. The resulting acetyl CoA can enter several pathways, but most often, it is delivered to the citric acid cycle for further catabolism.
During the conversion of pyruvate into the acetyl group, a molecule of carbon dioxide and two high-energy electrons are removed.
The carbon dioxide accounts for two of the six carbons of the original glucose molecule, and the electrons are picked up by NAD+ and carried as NADH to a later pathway for ATP production.