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Ordered: pfizerpen 600,000 units IM q12h. Available: pfizerpen 5

million units. directions: add 18.2 mL diluent to yield 500,000
units/mL. Add 3.2 mL diluent to yield 1,000,000 units/mL. If you
add 8.

User Matadur
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1 Answer

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Final answer:

To prepare a 600,000 unit IM dose of Pfizerpen from a concentration of 1,000,000 units/mL, after reconstitution with diluent, you would need to administer 0.6 mL of the solution. This calculation is crucial for proper dosing.

Step-by-step explanation:

The question is asking how to prepare a dose of Pfizerpen (penicillin G benzathine) at a concentration of 600,000 units intramuscularly (IM) every 12 hours, given that you have a vial of Pfizerpen 5 million units. The directions provided inform you how to dilute the medication to certain concentrations. To find the volume needed for a 600,000 unit dose from a 1,000,000 units/mL concentration, you would calculate as follows:

V = D/C

Where, V is the volume needed, D is the dose ordered, and C is the concentration after reconstitution.

Since the concentration we are using is 1,000,000 units/mL after adding 3.2 mL of diluent, the calculation for a 600,000 units dose would be:

V = 600,000 units / 1,000,000 units/mL

V = 0.6 mL

Therefore, you would administer 0.6 mL of the reconstituted solution to deliver a dose of 600,000 units of Pfizerpen. It is essential for healthcare providers to understand and accurately perform these calculations to ensure proper dosing and patient safety.

User Amit Mehta
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