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A healthy 43yr old man, on no medications, had the following results from test performed during private healthcare screening

Plasma
TB- 43umol/L (<20)
IB- 36umol/l (<5)
ALT- 21U/l (<42)
ALP- 126U/L (<250)
Alb- 40g/l ( 35-45)
GGT- 24( <55)
Urinary Bil.-Negative
Normal FBC, Retics, Haptoglobin and blood film.what disease is the person suffering from?

User Dwwork
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1 Answer

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Final answer:

The screening results indicate possible liver dysfunction or hemolysis due to elevated bilirubin levels. However, the normal range of other liver function tests suggests Gilbert's syndrome as a potential benign cause. A definitive diagnosis requires further evaluation and tests by a healthcare provider.

Step-by-step explanation:

The question concerns the interpretation of the results of a private healthcare screening for a healthy 43-year-old man. Considering the test results, which include an elevated plasma total bilirubin (TB) of 43 umol/L and indirect bilirubin (IB) of 36 umol/L, both higher than the reference ranges, there is an indication of possible liver dysfunction or hemolysis since other liver function tests such as alanine aminotransferase (ALT), alkaline phosphatase (ALP), albumin (Alb), and gamma-glutamyl transferase (GGT) are within normal ranges. Since the Full Blood Count (FBC), reticulocytes, haptoglobin, and blood film does not show abnormalities, an isolated rise in bilirubin without other signs of liver disease or hemolysis may suggest Gilbert's syndrome, which is a common but benign cause of mild unconjugated hyperbilirubinemia. However, without presenting symptoms or further tests to exclude other causes of elevated bilirubin such as liver diseases, hemolysis, or obstruction, a definitive diagnosis cannot be made based solely on these results. It is important that the patient consults with a healthcare provider for further evaluation, which may include additional tests like a direct antiglobulin test or liver ultrasound.

User Oli Folkerd
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