Final answer:
In asthmatic patients, there are higher levels of eosinophils, basophils, and mast cells, which contribute to the inflammatory response that leads to airway constriction.
Step-by-step explanation:
Patients with asthma tend to have higher levels of certain types of white blood cells, specifically eosinophils, basophils, and mast cells. Eosinophils are recruited during allergic reactions and release cytokines and inflammatory mediators.
contributing to the chronic inflammation seen in asthma. Basophils and mast cells are involved in hypersensitivity responses, and they release histamine, which leads to inflammation and constriction of airways in asthma patients.
Particularly, after an allergen exposure, T helper 2 (Th2) cells stimulate B cells to produce IgE antibodies, which then bind to receptors on mast cells.
Upon subsequent exposure to the allergen, these mast cells release histamine and other substances that precipitate the asthma response.