Final answer:
Long-term use of proton pump inhibitors can lead to osteoporosis due to reduced calcium absorption, increasing the risk of falls and subsequent fractures.
Step-by-step explanation:
People who are taking proton pump inhibitors (PPIs) for more than one year are at risk of osteoporosis, which is a condition characterized by weakened bones that are more susceptible to fractures. One of the complicating effects of osteoporosis is an increased risk of falls. The long-term use of PPIs may lead to decreased calcium absorption in the stomach because these drugs suppress the production of stomach acid, which is necessary for calcium absorption. This decreased calcium can contribute to the weakening of bones. Additionally, individuals with osteoporosis who experience falls can suffer from fractures, which can significantly impact their mobility and overall health.