185k views
2 votes
An adult male complains of fatigue abdominal pain and pallor.

his wbc is elevated with 10% immature granulocytes. his platelet
count is 780,000/uL. tear drops were seen in the smear. lap score
is 200.

1 Answer

5 votes

Final answer:

The case presents an adult male with symptoms and lab findings suggestive of a hematologic disorder, most likely a myeloproliferative disorder such as myelofibrosis, characterized by bone marrow fibrosis, anemia, elevated blood cell counts, and an enlarged spleen.

Step-by-step explanation:

An adult male with symptoms of fatigue, abdominal pain, and pallor, and laboratory findings of elevated white blood cell count with immature granulocytes (indicating possible left shift in WBC differentiation), elevated platelet count, and presence of tear drop cells on smear warrants consideration for a hematologic disorder. Your mention of a LAP score further supports this as the Leukocyte Alkaline Phosphatase score, which can be elevated in myeloproliferative disorders such as polycythemia vera or myelofibrosis. Here, a diagnosis of myelofibrosis may be particularly relevant, given the association with an enlarged spleen (which might explain the abdominal pain), raised platelet count, and characteristic tear-drop RBCs. Myelofibrosis is a serious bone marrow disorder that disrupts the body's normal production of blood cells, leading to extensive scarring in the bone marrow (fibrosis), resulting in anemia and other blood cell abnormalities.

User Rutruth
by
9.0k points