Question

Which statement describing systemic inflammatory response syndrome (SIRS) and/or multiple organ dysfunction

syndrome (MODS) is accurate?
a. MODS may occur independently from SIRS.
b. All patients with septic shock develop MODS.
c. The GI system is often the first to show evidence of dysfunction in SIRS and MODS.
d. A common initial mediator that causes endothelial damage leading to SIRS and MODS is endotoxin.

Answer 1

MODS may occur independently from SIRS, not all septic shock patients develop MODS, and endotoxin from gram-negative bacteria can initiate endothelial damage leading to SIRS and MODS.

Step-by-step explanation:

The accurate statement describing Systemic Inflammatory Response Syndrome (SIRS) and/or Multiple Organ Dysfunction Syndrome (MODS) is that MODS may occur independently from SIRS. This means that while SIRS can lead to MODS, MODS can also happen without the preceding SIRS phase. It's also important to note that not all patients with septic shock develop MODS. The gastrointestinal (GI) system is not necessarily the first to show evidence of dysfunction; it can vary by patient. Moreover, a common initial mediator that causes endothelial damage leading to SIRS and MODS is endotoxin, which is a component of the outer membrane of Gram-negative bacteria.