Final answer:
The level of hormone circulating in the bloodstream can influence the strength of the response in the receiving cell.
Step-by-step explanation:
One factor that might influence the strength of the response in the receiving cell is the level of hormone circulating in the bloodstream. If there is a significant level of a hormone, the target cells may decrease their number of receptors for that hormone, resulting in a decreased response.
On the other hand, if the level of the hormone is chronically reduced, target cells may engage in upregulation and increase their number of receptors, leading to a more sensitive response.