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Beta-oxidation of fatty acids, the TCA cycle, and carboxylation of pyruvate (gluconeogenesis) occur within which cellular compartment?

User Tiswas
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Final answer:

Beta-oxidation, the TCA cycle, and carboxylation of pyruvate (gluconeogenesis) all occur within the mitochondrial matrix, which is essential for the metabolism of fatty acids and production of energy.

Step-by-step explanation:

The beta-oxidation of fatty acids, the TCA (tricarboxylic acid) cycle, and the carboxylation of pyruvate (gluconeogenesis) occur within the mitochondrial matrix of a cell. During beta-oxidation, fatty acids are converted into fatty acyl CoA molecules in the cytoplasm and are then transported into the mitochondrial matrix, where they undergo further breakdown into acetyl CoA.

This acetyl CoA can then enter the TCA cycle, where it is oxidized to produce energy in the form of ATP. Pyruvate, which is formed during glycolysis in the cytoplasm, is also transported into the mitochondrial matrix, where it is transformed into acetyl CoA by the enzyme pyruvate dehydrogenase. In the case of gluconeogenesis, pyruvate undergoes carboxylation to form oxaloacetate, which can then be converted into glucose and other sugars.Beta-oxidation, the TCA cycle, and carboxylation of pyruvate (gluconeogenesis) all occur within the mitochondrial matrix, which is essential for the metabolism of fatty acids and production of energy.

User Lily Ballard
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