Final answer:
Leukotriene B4 (LTB4) stimulates neutrophil migration to sites of inflammation. It is part of the body's immune response, aiding in the fight against infections through the chemotaxis process.
Step-by-step explanation:
Leukotriene B4 (LTB4) stimulates neutrophil migration to sites of inflammation. LTB4 is a potent chemotactic agent that attracts neutrophils from the bloodstream to the site of infection or injury. This process is a critical component of the body's immune response, as neutrophils are primary phagocytes that ingest and eliminate pathogens. This recruitment of neutrophils is part of the larger inflammatory response, which is designed to contain and combat infections and facilitate tissue repair. Additionally, leukotrienes also increase vascular permeability, making it easier for leukocytes to move from the blood into the tissue space.
The chemotaxis process is guided by chemical signals released by injured cells, immune cells, and pathogens themselves. Neutrophils follow these chemical gradients towards the source of the signals. Once they arrive at the inflamed site, neutrophils are involved in phagocytosing pathogens and may also release enzymes and toxic substances to further combat the infection.