Final answer:
The most sensitive screening strategy for generalized malabsorption disorders is serological tests for the presence of primarily IgA antibodies to components of gluten, the transglutinaminase enzyme, and autoantibodies to endomysium.
Step-by-step explanation:
The most sensitive screening strategy for generalized malabsorption disorders is serological tests for the presence of primarily IgA antibodies to components of gluten, the transglutinaminase enzyme, and autoantibodies to endomysium. These tests are typically followed up with endoscopy and biopsy of the duodenal mucosa to confirm the diagnosis.