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What happens to the fat digestates once they enter the enterocyte and where does this occur?

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Final answer:

Fatty acids and monoglycerides from digested fat enter enterocytes in the small intestine, are recombined into triglycerides, and packaged with cholesterol into chylomicrons. These chylomicrons transport fats through the lymphatic system to the bloodstream, where they are eventually delivered to tissues like adipose tissue or organs such as the liver.

Step-by-step explanation:

Fate of Fat Digestates in Enterocytes

The digestion of fats by pancreatic lipases primarily occurs in the small intestine. Once the triglycerides are broken down into fatty acids and monoglycerides, they leave micelles and enter enterocytes, which are the epithelial cells lining the intestines. Within these cells, the fatty acids and monoglycerides are re-assembled into new triglyceride molecules. Along with cholesterol, these are then packaged into phospholipid vesicles known as chylomicrons. These chylomicrons are specially designed to transport fats through the aqueous environments of the lymphatic and circulatory systems. Chylomicrons exit the enterocytes via exocytosis, enter the lymphatic system through lacteals in the villi of the intestine, and are eventually released into the bloodstream. In the circulatory system, the chylomicrons transport fats to various tissues, such as the adipose tissue where they are stored as triacylglycerols, or to other organs like the heart, liver, and skeletal muscles.

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