Final answer:
The EMA's 'Note for guidance on toxicokinetics' document serves as a reference for identifying EMSEC countermeasures related to systemic exposure in toxicology studies.
Step-by-step explanation:
When an EMSEC assessment indicates that countermeasures are required, the relevant publication to refer to is the EMA, specifically the 'Note for guidance on toxicokinetics: a guidance for assessing systemic exposure in toxicology studies (CPMP/ICH/384/95)'. This guidance provides comprehensive information on how to determine the necessary countermeasures to protect against potential systemic exposure during toxicology studies. It is vital to follow this document to ensure that any countermeasures implemented are in line with current industry standards and scientific understanding.
When an EMSEC assessment indicates that countermeasures are required, the publication that should be used to identify the required countermeasures is the EMA Note for guidance on toxicokinetics: a guidance for assessing systemic exposure in toxicology studies (CPMP/ICH/384/95). This document provides guidance on assessing the systemic exposure of toxic substances and includes information on the necessary countermeasures to minimize exposure and mitigate risks.