Question

A 23 year old woman presents with a two week history of bloody discharge from her right breast. Family history is significant for a 58 year old aunt who was recently diagnosed with breast cancer. On physical examination, the right breast is slightly tender to palpation in the area of the nipple. There are no masses, and the skin shows no dimpling, retractions, or inflammatory changes. There is no axillary adenopathy. Urine beta-hCG is negative. Which of the following is the most likely diagnosis in this patient?

A. Intraductal papilloma
B. Infiltrating ductal carcinoma
C. Acute mastitis
D. Paget's disease of the breast
E. Fibroadenoma"

Answer 1

The most likely diagnosis in this patient is Paget's disease of the breast (D). Paget's disease of the breast is a rare form of breast cancer that begins in the milk ducts and spreads to the skin of the nipple and areola.

Step-by-step explanation:

The most likely diagnosis in this patient is Paget's disease of the breast (D). Paget's disease of the breast is a rare form of breast cancer that begins in the milk ducts and spreads to the skin of the nipple and areola. It often presents with symptoms such as nipple discharge, skin changes, and nipple sensitivity or tenderness. In this case, the patient's history of bloody discharge, along with the tenderness and absence of other findings, is suggestive of Paget's disease.