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A 52 year old female comes in for a yearly physical. She has been feeling completely well, and denies chest pain, shortness of breath, weight loss, decreased exercise tolerance, or change in stool frequency or caliber. Past medical history is significant for hypertension controlled with hydrochlorothiazide. Although she has a history of several abnormal Pap smears thirty years ago, her tests have been normal since then, with her last normal Pap occurring two years ago. She had a normal mammogram earlier this year. She has smoked one half a pack of cigarettes daily for thirty-five years, and drinks 1-2 glasses of wine nightly. Her mother died at age 63 from ovarian cancer, and her father died at age 70 from lung cancer. Her siblings are alive and well. EKG shows sinus rhythm with a normal axis and intervals. Of the following, which is the most appropriate screening test to offer this patient?

A. Pap smear
B. CA-125
C. CXR
D. Exercise stress test
E. Colonoscopy

1 Answer

7 votes

Final answer:

The most appropriate screening test to offer this patient would be a CA-125 test.

Step-by-step explanation:

Based on the given information, the most appropriate screening test to offer this patient would be a CA-125 test. The CA-125 blood test is used to detect ovarian cancer in women who have a higher risk of developing the disease, such as those with a family history of ovarian cancer or certain genetic mutations. Given that the patient's mother died from ovarian cancer, it is important to screen for this specific type of cancer.

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