Final answer:
Histamine and serotonin are the two chemical mediators involved in anaphylaxis. They cause bodily changes such as blood vessel dilation, low blood pressure, hives, and difficulty breathing.
Step-by-step explanation:
The two chemical mediators involved in anaphylaxis are histamine and serotonin. During anaphylaxis, these chemicals cause various bodily changes. Histamine causes blood vessels to dilate, which leads to a drop in blood pressure and the development of hives. It also causes smooth muscles in the lungs to contract, resulting in difficulty breathing. Serotonin contributes to the constriction and dilation of blood vessels and enhances the release of other chemical mediators.