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Use mono- to build a word that means pertaining to one nucleus:

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Final answer:

The term 'mononuclear' is formed by combining the prefix mono- with nuclear, indicating a single nucleus.

Step-by-step explanation:

The word constructed from mono-, meaning 'one', and pertaining to the nucleus, which houses the cell's DNA, is mononuclear. This term refers to something consisting of a single nucleus. In biological contexts, mononuclear cells in the bloodstream, for instance, have one nucleus, and this term can distinguish them from polynuclear (multinucleated) cells.

The prefix mono- is also seen in words like monomer, which is a single subunit that can be bonded with other identical molecules to form a polymer, as seen in nucleic acids where a nucleotide acts as a monomer. The word that means pertaining to one nucleus is Mononuclear. This term is commonly used in biology to describe a cell or organism that has only one nucleus. For example, red blood cells are mononuclear, as they contain only one nucleus.

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