Final answer:
Ethical principles in research aim to balance the need for individual autonomy and subject protection with the pursuit of scientific knowledge, ensuring participants' dignity, safety, and beneficence while promoting justice in healthcare practices.
Step-by-step explanation:
The ethical principles used in research seek to balance individual autonomy and the protection of research subjects with the advancement of science. Ensuring that studies are conducted with integrity, respect for human dignity, and concern for safety are paramount. Researchers must also navigate the principle of beneficence, which means acting in ways that benefit others, and the principle of justice, which pertains to the equitable distribution and practice of healthcare.
Informed consent is a critical aspect, ensuring that participants are aware of the study's purpose and potential risks. Respect for privacy, honesty in communication, and ethical treatment of animals used in research are also essential. Institutional Review Boards (IRBs) play a significant role in reviewing research proposals to verify that ethical standards are met and maintain the balance between research objectives and the ethical treatment of subjects. Clinical equipoise and justice are principles that guide the conduct of randomized trials.