Final answer:
Sickle cell anemia is a genetic disorder that can trigger a sickle crisis in individuals under certain conditions. These conditions include hypoxia, dehydration, or acidosis, which reduce the ability of sickle-shaped red blood cells to deliver oxygen to tissues and can cause blockages in capillaries.
Step-by-step explanation:
Sickle cell anemia is a genetic disorder caused by the production of abnormal hemoglobin, resulting in the characteristic sickle-shaped red blood cells. A sickle crisis can be triggered by conditions such as hypoxia (low oxygen levels), dehydration, or acidosis (low pH levels). These conditions reduce the ability of the sickle-shaped red blood cells to deliver oxygen to tissues, causing them to become stuck in narrow capillaries and blocking blood flow.