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Consider a juxtamedullary nephron. A single NaCl pump in the ________ of the loop of Henle is able to produce a concentration difference of ___________ between the inside and outside of the tubule.

User Dilletante
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Final answer:

In the juxtamedullary nephron, a single NaCl pump in the thick ascending limb of the loop of Henle actively transports ions to create a significant osmolarity difference that helps concentrate urine.

Step-by-step explanation:

Considering a juxtamedullary nephron, a single NaCl pump in the thick ascending limb of the loop of Henle is able to produce a concentration difference. This concentration difference is key to the countercurrent multiplication mechanism that the kidney uses to concentrate urine. In the ascending limb, Na+ and Cl- ions are actively reabsorbed by a cotransport system. This system is capable of producing a difference in osmolarity between the inside and outside of the tubule, which contributes to the generation of a hyperosmotic environment in the kidney medulla and a hypoosomotic filtrate by the time it reaches the distal convoluted tubule (DCT).

User Abhinavsinghvirsen
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