Final answer:
The hypothalamus is the brain region responsible for appetite control, regulating homeostasis via the autonomic and endocrine systems.
Step-by-step explanation:
The primary center for appetite control in the brain is the hypothalamus. This region is located inferior and slightly anterior to the thalamus and is responsible for regulating homeostasis including appetite through the autonomic and endocrine systems. The hypothalamus manages a collection of nuclei that integrate various hunger and satiety signals which in turn, determine whether or not we engage in feeding behavior.