Final answer:
The question addresses the need for investigators to have appropriate accommodations for illiterate or blind participants in studies, drawing a parallel with past discriminatory literacy tests in Mississippi.
Step-by-step explanation:
The question discusses the ethical considerations an investigator ought to have in accommodating participants who are illiterate or blind in research studies. This scenario is analogous to historic instances, such as in Mississippi, where literacy tests were used to disenfranchise voters, particularly targeting black communities. It reflects upon the biased application of these tests, where illiterate whites were often allowed to pass, while highly educated blacks were rejected. This historical context is vital for understanding how current research practices should be designed inclusively, ensuring accessibility for all participants regardless of literacy or visual impairments.