Final answer:
In hypercortisolism, cortisol has an effect on calcium balance, causing b) negative calcium balance.
Step-by-step explanation:
Hypercortisolism refers to abnormally high levels of cortisol in the body. In hypercortisolism, cortisol has an effect on calcium balance, causing negative calcium balance.
High levels of cortisol decrease the absorption of calcium from the gastrointestinal tract and reduce the production of new bone. This can lead to a loss of calcium from the bones and result in negative calcium balance.