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There are three major subpopulations of helper T cells- TH1, TH2, and TH17

TH1 cells are stimulated by interleukin-12 (IL-12) and secrete interferon-γ (IFN-γ) in response. They generally promote cell-mediated responses

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Final answer:

Helper T cells are a type of T lymphocyte that play a crucial role in the immune response. TH1 cells are stimulated by interleukin-12 (IL-12) and secrete interferon-γ (IFN-γ) to enhance cell-mediated responses. They promote the activities of macrophages, cytotoxic T cells, and natural killer (NK) cells.

Step-by-step explanation:

Helper T cells are a type of T lymphocyte that play a crucial role in the immune response. There are three major subpopulations of helper T cells: TH1, TH2, and TH17. TH1 cells are stimulated by interleukin-12 (IL-12) and secrete interferon-γ (IFN-γ) in response. They generally promote cell-mediated responses, enhancing the activities of macrophages, cytotoxic T cells, and natural killer (NK) cells. Helper T cells are a type of T lymphocyte that play a crucial role in the immune response.

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