Final answer:
Tubercules and slime found in clinical samples should be tested for acid-fast bacilli such as Mycobacterium tuberculosis using the Ziehl-Neelsen staining technique, with further confirmation via culturing or nucleic acid amplification tests.
Step-by-step explanation:
Diagnosis of Tubercles and Slime Presence
When tubercules and slime are found in clinical samples, they shall be tested for the presence of acid-fast bacilli such as Mycobacterium tuberculosis, which is the bacterium that causes tuberculosis (TB). Samples such as sputum or other bodily fluids are stained using the Ziehl-Neelsen technique to detect these bacilli. Confirmation of the presence of M. tuberculosis is achieved by culturing the organism or by using nucleic acid amplification tests (NAATs) that identify the bacterial DNA. Additionally, if diagnoses such as tuberculoid leprosy are suspected, a skin biopsy would be performed to look for the causative agent Mycobacterium leprae. It's important to note that diseases like brucellosis and tularemia involve different pathogens and have different testing protocols such as agglutination tests or ELISAs.