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Botulinum toxin is used in a clinical setting to weaken muscle for treating spasms and neurological movement disorders. It is also used in cosmetic procedures to prevent wrinkles by paralyzing facial muscles. It is a powerful neurotoxin produced by the bacterium Clostridium botulinum and related species.

How does it work?

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Final answer:

Botulinum toxin, or Botox, inhibits the release of acetylcholine at the neuromuscular junction, causing muscle paralysis. In small, controlled amounts, it is used to relax muscles for medical and cosmetic purposes, including treating wrinkles and muscle spasms.

Step-by-step explanation:

Botulinum toxin, commonly known as Botox, functions by inhibiting muscle contractions. It acts at the neuromuscular junction where it blocks the release of the neurotransmitter acetylcholine. This action results in paralysis of the muscle, which, when utilized in controlled amounts, can be beneficial for various medical and cosmetic purposes. Botulinum toxin is produced by the bacterium Clostridium botulinum and is considered extremely potent. In a clinical setting, it assists in the treatment of conditions like cervical dystonia, eye twitches, and excessive sweating by causing the involved muscles to relax. As it prevents nerve signals from reaching muscles, the toxin finds uses in reducing the appearance of wrinkles in cosmetic procedures.

The substance is a combination of a light A subunit and a heavy protein chain B subunit, with the B subunit allowing for attachment to neurons. After entering the neurons, the A subunit acts as a protease, cleaving proteins that are crucial to acute acetylcholine release. This interferes with normal neuronal transmission and causes muscles to remain relaxed. Therefore, repeated injections may be necessary every few months to maintain the therapeutic or cosmetic effects, given that the treatment is not permanent.

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