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What is the functional role of platelet-derived growth factor (PDGF)?

User Bdereta
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Final answer:

Platelet-derived growth factor (PDGF) is essential for regulating cell growth, wound healing, and tissue repair by stimulating cell proliferation, migration, adhesion, and angiogenesis.

Step-by-step explanation:

The functional role of platelet-derived growth factor (PDGF) is to regulate cell growth, wound healing, and tissue repair. Similar to the epidermal growth factor (EGF), PDGF is involved in stimulating various key cellular processes including cell proliferation, cell migration and adhesion, and angiogenesis, which is the growth of new blood vessels. This is critical in areas where the body has sustained injury and requires an organized influx of cells to repair tissues. Additionally, platelets play an essential role in hemostasis by stopping blood flow following vessel damage and secreting growth factors necessary for the growth and repair of tissue, particularly connective tissue. Therapies involving concentrated platelet infusions utilize PDGF to stimulate healing in certain medical conditions.

PDGF stimulates cell proliferation, which is the division of cells to create new ones. It also promotes cell migration and adhesion, which is the movement and attachment of cells. Additionally, PDGF stimulates angiogenesis, which is the growth of new blood vessels.

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