Final answer:
The best reason for using specific gloves to handle DCM during Solid-Liquid Extraction is to protect against its ability to penetrate skin, with nitrile gloves being a suitable choice due to their chemical resistance.
Step-by-step explanation:
The best reason for the glove choice used to handle dichloromethane (DCM) during a Solid-Liquid Extraction process is to provide protection against the solvent's ability to penetrate skin and potentially cause harm. This is particularly important given that DCM is a volatile organic compound that can easily pass through some types of gloves. Therefore, chemically resistant gloves, such as those made from materials like nitrile, are recommended for handling DCM to ensure safety during laboratory procedures such as Solid-Liquid Extraction of tablets. The gloves should be selected based on compatibility with DCM, which often depends on the glove material's resistance to chemical solvents.