Final answer:
The Clayton Antitrust Act passed in the first months of Woodrow Wilson's administration with the goal to stop the creation of monopolies by increasing the federal government's power to regulate big business.
Step-by-step explanation:
The act that passed in the first months of Woodrow Wilson's administration with the goal to stop the creation of monopolies by increasing the federal government's power to regulate big business was the Clayton Antitrust Act. This act expanded on the provisions of the previous Sherman Antitrust Act and allowed for the investigation and dismantling of more monopolies. It also targeted interlocking directorates, where competing companies operated together to restrain trade.