Final answer:
The statement that EPSP is much larger than EPP is false. EPPs typically trigger an action potential every time, whereas EPSPs may require summation to reach the action potential threshold.
Step-by-step explanation:
The statement that the EPSP is much larger than the EPP is false. An excitatory postsynaptic potential (EPSP) and an end-plate potential (EPP) are not directly comparable in terms of size because they occur in different contexts. The EPSP is a depolarizing presynaptic potential that can lead to an action potential if it reaches the threshold. The EPP, on the other hand, is the depolarization of the skeletal muscle endplate on a neuromuscular junction and is typically large enough to always reach the threshold and trigger an action potential. In summation, multiple EPSPs may be required to depolarize the postsynaptic neuron above the threshold for an action potential to occur, depending on the net effect of excitatory and inhibitory inputs.