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Platelet membranes contain binding sites for the soluble plasma protein ______ as well as for the insoluble fibrous protein _____, formed by the activation of clotting factors.

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Final answer:

Platelet membranes have binding sites for fibrinogen and fibrin, respectively, which are integral to the blood clotting process. Fibrinogen is converted to fibrin at the site of injury by clotting factors, and vitamin K is vital for clotting factor production.

Step-by-step explanation:

Platelet membranes contain binding sites for the soluble plasma protein fibrinogen as well as for the insoluble fibrous protein fibrin, formed by the activation of clotting factors.

Platelets play a crucial role in blood clotting by adhering to the site of injury and forming a plug to prevent bleeding. The soluble protein fibrinogen in the plasma gets converted into the insoluble protein fibrin by the action of clotting factors, including thrombin. This conversion is pivotal in the coagulation process, as fibrin forms a mesh that solidifies the platelet plug, effectively sealing the wound.
Clotting factors, including calcium (factor IV) and vitamin K, are essential in this process, with the liver being the prime producer of these factors. A deficiency in vitamin K can lead to impaired blood clotting. Platelets contain glycoproteins that can recognize and bind to fibrinogen and von Willebrand factor, aiding in the stabilization of the growing platelet plug.

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