Final answer:
Depolarisation is when the interior of the cell becomes less negative due to the influx of Na+ ions.
Step-by-step explanation:
Depolarisation occurs when the interior of the cell becomes less negative due to the influx of Na+ ions. When a stimulus causes the membrane to become permeable to Na+, Na+ ions rush into the cell, resulting in depolarization. This is a critical step in the generation of an action potential in a neuron.