Final answer:
After phagocytosis, a lysosome fuses with the vacuole to digest the material, followed by the excretion of debris through exocytosis. Option B is correct.
Step-by-step explanation:
Once solid material is phagocytized and taken into a vacuole, the best description of what happens next is that a lysosome combines with the vacuole and digests the enclosed solid material. This process occurs when a pathogen such as a bacterium is engulfed by a cell through its plasma membrane, forming a vesicle known as a phagosome. The phagosome then fuses with a lysosome, creating a phagolysosome where digestive enzymes and acids from the lysosome break down the pathogen. Eventually, the soluble debris from the destroyed pathogen is excreted from the cell through exocytosis.