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Which of the following tests are useful in diagnosing depression?

1. Coagulation profile and protein uptake test
2. Dexamethasone suppression test (DST)
3. Amitriptyline level
4. Creatinine and thyroid-stimulating hormone levels

User Ali Mezal
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1 Answer

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Final answer:

The Dexamethasone suppression test (DST) was historically used for depression diagnosis, but now Creatinine and thyroid-stimulating hormone levels are more common to rule out thyroid dysfunction. Amitriptyline level tests are useful to monitor medication levels in treatment. The correct option is 2.

Step-by-step explanation:

When considering tests that could be useful in diagnosing depression, it's important to understand that there isn't a definitive laboratory test for depression. Instead, the diagnosis is typically based on a thorough psychiatric evaluation. However, some tests are occasionally used to rule out other conditions that might cause symptoms of depression or to monitor treatment efficacy.

  • The Dexamethasone suppression test (DST) is an example that was historically used to detect changes in cortisol secretion which could be associated with depression, but it is not commonly used today due to lack of specificity.
  • Assessing Amitriptyline levels can be useful when an individual is being treated with this medication, ensuring therapeutic levels are maintained and avoiding toxicity.
  • Checking Creatinine and thyroid-stimulating hormone (TSH) levels is also common, as thyroid dysfunction can mimic or exacerbate depressive symptoms.

Coagulation profile and protein uptake tests are not typically associated with the diagnosis of depression. The key in managing depression is a comprehensive approach that may involve psychotherapy, antidepressant medications, and lifestyle modifications tailored to the individual's needs.

User Rajesh Batth
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