Final answer:
Pathological protein excretion is generally considered to be above 200 milligrams per day, with amounts exceeding 300 mg/day being clinically significant and an indicator of possible kidney damage or glomerular dysfunction.
Step-by-step explanation:
When evaluating urinary protein excretion, trace amounts of protein are normally found in the urine, with about 10 mg/100 mL being acceptable in a random urine sample without being considered pathological. Protein excretion above this threshold could indicate damage to the glomerular capillaries, a condition that might warrant medical attention. An excessive amount of protein in the urine usually suggests that the glomerulus is defective, allowing proteins to leak into the filtrate, which is a sign of underlying renal pathology.
The typical daily protein excretion rate in a normal individual ranges from 150 to 200 milligrams. However, protein excretion exceeding 200 milligrams per day is often regarded as abnormal or pathological. Specifically, protein excretion beyond 300 mg/day is clinically significant and referred to as proteinuria, which calls for further clinical assessment and possible intervention.