Final answer:
The creatinine clearance, calculated using given urine and serum creatinine concentrations along with urine volume and body surface area, is 65 mL/min after adjustment for body surface area.
Step-by-step explanation:
The direct answer in 2 lines to the given question about the creatinine clearance (CCr) calculation is: The creatinine clearance is 65 mL/min, which is corrected for body surface area (BSA).
The explanation in 200 words involves using the standard formula for creatinine clearance (CCr), which is the product of urine concentration (U) and urine volume (V), divided by serum concentration (B). Using the values provided:
- Urine concentration (U) = 84 mg/dL
- Urine volume (V) for 24 hrs = 1440 mL -> for 1 min = 1 mL/min (since 1440 mL/24 hr = 1440 mL/1440 min)
- Serum concentration (B) = 1.4 mg/dL
The creatinine clearance (uncorrected) is therefore calculated as:
CCr (uncorrected) = (U x V) / B = (84 mg/dL x 1 mL/min) / 1.4 mg/dL = 60 mL/min
The correction for BSA is carried out using the patient's BSA and the average BSA using the following formula:
CCr-corrected = CCr (uncorrected) x (patient BSA / average BSA)
CCr-corrected = 60 mL/min x (1.60 m2 / 1.73 m2) = 65 mL/min
This value is within the normal range of creatinine clearance for adults, indicating that this person's kidneys are functioning well.