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True or False? It is easier to denature DNA with a lot of Cytosine-Guanine bonds at lower temperatures because it has more hydrogen bonds than the Adenine-Thymine bonds.

User JDawwgy
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Final answer:

The assertion that DNA with a higher C-G content is easier to denature at lower temperatures is false because C-G bonds are stronger than A-T bonds, requiring higher temperatures for denaturation. The corresponding sequence to 'ATTG' is 'TAAC' based on complementary base pairing rules.

Step-by-step explanation:

The statement regarding DNA denaturation and the hydrogen bonds in Cytosine-Guanine (C-G) pairs is false. The C-G base pairs form three hydrogen bonds, compared to the two hydrogen bonds that Adenine-Thymine (A-T) pairs form. Therefore, the presence of more C-G bonds means DNA is more stable and requires higher temperatures to denature, because these three bonds are stronger and more numerous than the two bonds between A-T pairs. To answer the student's question on the sequence that complements 'ATTG', you just need to apply the base pairing rules where A pairs with T, and C pairs with G. Consequently, the sequence that pairs with 'ATTG' on the other DNA chain is 'TAAC'.

To summarize, while both sequences are crucial for DNA stability and function, it is the adenine and thymine that are less stable compared to guanine and cytosine due to fewer hydrogen bonds. More hydrogen bonds means stronger attraction between the strands, thus it does not make it easier to separate the strands at lower temperatures. So in fact, DNA regions with high GC content are more difficult to denature. Higher the GC content, the higher the required temperature for denaturation.

It is false that DNA with more Cytosine-Guanine bonds is easier to denature at lower temperatures; it's the opposite as these bonds are stronger. The sequence that pairs with 'ATTG' is 'TAAC', adhering to the base pairing rules of A with T and C with G.

User Canolucas
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