Final answer:
Microscopic colitis is linked to long-term use of nonsteroidal anti-inflammatory drugs (NSAIDs) and proton pump inhibitors (PPIs). These medications contribute to inflammation of the colon and are part of a broader group of conditions known as inflammatory bowel diseases, managed by lifestyle modifications and various medications.
Step-by-step explanation:
Microscopic colitis is associated with long-term use of several drug classes, specifically nonsteroidal anti-inflammatory drugs (NSAIDs) and proton pump inhibitors (PPIs). These medications can lead to inflammation of the colon at a microscopic level, hence the name microscopic colitis. NSAIDs are commonly used for pain and inflammation, but their prolonged use can cause gastrointestinal irritation and damage. Similarly, while PPIs are used to reduce stomach acid production and are helpful in treating conditions like GERD, long-term use has been linked to various gastrointestinal side effects, including microscopic colitis.
Microscopic colitis is part of inflammatory bowel diseases, which are typically characterized by chronic inflammation of the digestive tract. Lifestyle changes, such as reducing the consumption of animal protein and alcohol, along with specific medications, can help manage the symptoms and maintain remission. Surgical intervention may be required in extreme situations. Appropriate management and treatment of diseases such as microscopic colitis depend on an understanding of the contributing causes.