Final answer:
In synapses between neurons, the synaptic change rules due to co-activity can differ significantly, influenced by neurotransmitters like glutamate and GABA, which help maintain the excitatory-inhibitory balance critical for brain function.
Step-by-step explanation:
For any two connected neurons, the co-activity rules for synaptic change may vary greatly. Synaptic changes are influenced by co-activity between neurons, where changes in synaptic strength occur due to neurotransmitter release and post-synaptic response.
In the case of a chemical synapse, the connection involves neurotransmitter diffusion across a short distance, leading to the potential summation of post-synaptic potentials. This summation can lead to reaching a threshold potential that initiates further neuronal activity.
It's important to understand that the regulation of neuronal networks depends significantly on the correct balance of excitatory and inhibitory signals. The neurotransmitters glutamate and GABA play critical roles in this regulation through pyramidal cells and interneurons in the cerebral cortex. The healthy functioning of these neuronal circuits is essential in preventing neuropsychiatric and ischemic conditions.