Final answer:
Endogenous opioids correlate with higher pain tolerance, and Naloxone is used to block opioid receptors during an overdose. Opioids include drugs like heroin, morphine, and oxycodone, and though they are effective painkillers, they carry a high risk of abuse.
Step-by-step explanation:
Endogenous opioids are known to be correlated with higher pain tolerance. Naloxone is a drug that blocks opioid receptors binding cites, which can be used to stop ODs from heroin. Opioids such as heroin, morphine, methadone, and codeine are types of drugs derived from opium and have analgesic properties.
They reduce pain by mimicking the body's own painkilling mechanism, but due to their euphoric effects, they have a high potential for abuse. Drugs like hydrocodone and oxycodone are prescription pain relievers that have been a significant public health concern due to misuse and abuse.
Morphine and codeine, obtained from the opium poppy plant, serve as painkillers, with heroin being a highly addictive derivative of morphine. OxyContin is structurally similar to heroin and induces similar physiological effects. The administration of these powerful opioid drugs changes how pain is experienced by attaching to specific receptors in the brain and other parts of the body.