Final answer:
Edema of the hands, face, feet, and legs is not typically an early sign of pregnancy but rather a symptom that can appear in the later stages due to increased bodily fluids.
Step-by-step explanation:
The question asks which of the following is not an early sign of pregnancy: a) edema of the hands, face, feet, and legs, b) breast tenderness, c) morning sickness, or d) a missed menstrual period. The early signs of pregnancy often include a missed menstrual period, breast tenderness, and morning sickness, which can occur at any time of day and might include nausea and vomiting. However, edema of the hands, face, feet, and legs is typically not an early sign of pregnancy; it is more common in the later stages of pregnancy due to increased body fluids and can be associated with other conditions.