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What is responsible for orienting both tRNAs for the peptidyl transferase reaction to occurs?

User Markiv
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Final answer:

The ribosomal RNA (rRNA) component known as the 23S rRNA is responsible for orienting both tRNAs for the peptidyl transferase reaction to occur.

Step-by-step explanation:

The peptidyl transferase reaction, a crucial step in protein synthesis, is facilitated by the ribosome, a complex molecular machine composed of RNA and proteins. Specifically, the 23S rRNA within the large ribosomal subunit plays a central role in orienting both transfer RNA (tRNA) molecules involved in the reaction. The 23S rRNA forms the peptidyl transferase center, where the actual peptide bond formation takes place. Its precise structure and chemical properties guide the positioning of the aminoacyl (A) and peptidyl (P) tRNA molecules, ensuring the correct alignment for the catalysis of the peptide bond formation during translation.

Understanding the molecular interactions orchestrated by the 23S rRNA sheds light on the intricate mechanisms governing protein synthesis. The ribosomal RNA's active participation in positioning tRNAs underscores its essential role in orchestrating the key steps of translation.

The 23S rRNA, a component of the large ribosomal subunit, serves as the molecular architect guiding the orientation of tRNAs for the peptidyl transferase reaction. Appreciating the role of 23S rRNA enhances our comprehension of the intricate molecular processes underlying protein synthesis.

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