Final answer:
Phospholipids in eukaryotic cells are synthesized by enzymes on the cytosolic face of the endoplasmic reticulum, particularly the smooth endoplasmic reticulum, which is involved in lipid synthesis.
Step-by-step explanation:
In eukaryotic cells, phospholipids are synthesized by enzymes bound to the cytosolic face of the endoplasmic reticulum (ER). Specifically, these enzymes are associated with the smooth endoplasmic reticulum (SER), which is involved in the synthesis of lipids, including phospholipids, as well as cholesterol and steroid hormones. The smooth ER is also crucial for detoxification processes and storage of calcium ions. Phospholipids are essential components of the plasma membrane, creating a bilayer that is selectively permeable and capable of self-repair and fluid movement within the membrane, according to the fluid mosaic model.