Final answer:
An increase in dopamine activity is associated with the development of schizophrenia, a mental illness managed with medications that block dopamine receptors.
Step-by-step explanation:
The increase in dopamine activity plays a significant role in the development of schizophrenia. Schizophrenia is a mental illness with symptoms that include hallucinations, delusions, and difficulty in differentiating between reality and imagination. The disease is often managed with antipsychotic medications that work by blocking dopamine receptors, which emphasizes the relevance of dopamine in its pathology. On the other hand, diseases like Parkinson's disease are associated with a loss of dopamine-producing neurons, which is why treatments aim to increase dopamine levels. This neurodegenerative disease causes motor symptoms that worsen over time due to the progressive loss of dopamine neurons.