Final answer:
In Shirley Jackson's 'The Lottery', Tessie's final scream challenges the unfairness and injustice of the lottery itself. She questions the tradition and cruelty of stoning someone to death based on a random draw, exposing the blind acceptance of the villagers towards this annual ritual.
Step-by-step explanation:
The significance of Tessie's final scream, 'It isn't fair, it isn't right,' in Shirley Jackson's 'The Lottery' lies in the challenge she makes to the unfairness and injustice of the lottery itself. Tessie questions the tradition and the cruelty of stoning someone to death based on a random draw. By explicitly challenging the lottery, Tessie exposes the blind acceptance of the villagers towards this annual ritual.
The aspect of the lottery that Tessie explicitly challenges is the idea that it is fair and justifiable. She questions the very foundation of the lottery and challenges the belief that it is acceptable to kill someone simply because their name is drawn. However, Tessie's scream does not question the other aspects of the lottery, such as the participation of every villager and the sense of community that it brings.