Final answer:
Upcountry settlers faced the issue of Antifederalist skepticism during the ratification of the U.S. Constitution, leading many to refuse to attend the special ratification conventions.
Step-by-step explanation:
The problem faced by upcountry settlers during the ratification of the United States Constitution was due to the Antifederalist sentiment that arose because the ratification process for the Constitution involved special conventions rather than state legislatures. They were concerned that the new federal government would have too much centralized power, and many upcountry settlers did not attend the ratification conventions because of these apprehensions.
The correct answer to the question would be that the upcountry settlers refused to attend the convention (C). The historical context of this situation reveals that it was largely driven by the fear of a strong central government and the refusal to submit the document to the state legislatures, a strategic move by the Founding Fathers to ensure the adoption of a new, more powerful federal government.