Final answer:
Human activities can cause great destruction on Earth's subsystems. Changes on a global scale, such as depletion of the ozone layer, desertification, topsoil loss, and global climate change, are caused by human activities.
Step-by-step explanation:
Human activities can indeed cause great destruction on Earth's subsystems. Changes on a global scale, such as depletion of the ozone layer, desertification, topsoil loss, and global climate change, are caused by human activities. Additionally, the alteration of ecosystems to the point where some may be in danger of collapse is a direct result of human technology and the harnessing of fossil fuels.