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Dentify the functions of an enhancer in transcription.

A)A cis-acting regulatory sequence of DNA that A cis-regulatory reduces levels of transcription.
B) A-cis regulatory element that regulates gene transcription in specific tissues or cells. C) Begins gene expression by disabling repressors and binding to the repressor elements.
D) Inhibits transcription by binding to the operator.
E)Regulates transcription by catalyzing the formation of an enhanceosome, activating transcription.

User Sanjeet A
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Final answer:

An enhancer is a cis-acting regulatory DNA element that binds transcription factors to increase the transcription rate of a gene. Though they can be located far from the gene they regulate, their interactions with transcription machinery enhance gene expression. The correct function of an enhancer corresponds to the option that describes its role in regulating gene transcription in specific tissues or cells.

Step-by-step explanation:

Enhancers are critical regulatory elements in DNA that increase the transcription of a gene. They are considered cis-acting elements because they are located on the same chromosome as the gene they regulate. Enhancers can be found in various locations with respect to the gene; they might be upstream or downstream, in non-translated regions, or even within introns. The key role of an enhancer is to bind specific transcription factors and through a DNA bending protein, bring these factors in close proximity to the promoter of the gene. This interaction facilitates a higher rate of transcription initiation by making the promoter more accessible to the RNA polymerase enzyme.

Activators can bind to the enhancer's distal control elements, which then interact with mediator proteins and general transcription factors at the promoter. This complexity allows enhancers to exert tissue-specific or temporally-controlled gene expression, enabling differential gene expression while using the same promoter.

The correct response based on the provided information is B) A cis-regulatory element that regulates gene transcription in specific tissues or cells, as enhancers modulate the efficiency and rate of gene transcription, and are not directly involved in silencing, initiating gene expression by disabling repressors, or inhibiting transcription as described in the other options.

User Gavriel Cohen
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